|
Characteristics of newborns treated with ketorolac and historic controls. |
|||
| Historic controls |
Ketorolac |
p** |
|
| Year 1999 – 2000 |
Year 2001–2002 |
||
| N = 35† |
N = 43† |
||
| n(%) |
n(%) |
||
|
|
|||
| Dead before discharge* |
18 (34.0) |
16 (27.1) |
0.54 |
| Birthweight (g) |
0.28 |
||
| <= 750 |
4 (11.4) |
8 (18.6) |
|
| 751–1000 |
13 (37.1) |
9 (20.9) |
|
| 1001–1250 |
18 (51.4) |
26 (60.59 |
|
| Apgar Score < 6 at 5 minutes |
10 (28.6) |
11 (25.5) |
0.80 |
| Oxygen (days) |
0.01 |
||
| 0–10 |
9 (25.7) |
21 (48.8) |
|
| 11–27 |
10 (28.6) |
15 (34.9) |
|
| >= 28 |
16 (45.7) |
7 (16.3) |
|
| Sepsis |
16 (45.7) |
24 (55.8) |
0.50 |
| Peri–intraventricular hemorrhage > grade III |
8 (22.9) |
6 (14.0) |
0.38 |
| Necrotizing Enterocolitis >= II degree |
5 (14.3) |
9 (20.9) |
0.56 |
|
† Excludes newborns that died before discharge. * N = 53 in historic controls group and N = 59 in ketorolac group, that includes all eligible live newborn during the study period. ** P-value Fisher exact test. | |||
Avila-Vazquez et al. BMC Pediatrics 2004 4:15 doi:10.1186/1471-2431-4-15 |
|||