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Clinical and microbiological details of 52 children with suspected CNS infection and 43 with meningococccal septicaemia |
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| Initial Clinical Impression |
LP Performed |
LP Not performed |
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|
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| No. of patients |
CSF findings and microbiology results |
No. of patients |
Microbiology results |
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|
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|
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| Suspected meningoencephalitis, no rash |
14 |
Pleocytosis, N. meningitidis in CSF [2]* |
8 |
N. meningitidis in BC & PCR [1] |
| Pleocytosis, N. meningitidis in BC [1] |
N. meningitidis by PCR [1] |
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| Pleocytosis, E. coli in CSF [1] |
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| Pleocytosis, cultures negative [2] |
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| Suspected meningitis with meningococcal rash |
1 |
Pleocytosis, cultures negative [1] |
12# |
N. meningitidis in BC (6, including 4 PCR +) |
| N. meningitidis by PCR [2] |
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| H. Influenzae in endotracheal aspirate [1] |
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| Septic screen in infants <6 months old |
10 |
CSF normal |
7 |
E. coli in BC [1] |
| Meningococcal septicaemia (LP Contraindicated) |
0 |
43 |
N. meningitidis in BC (7, including 5 PCR +) |
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| N. meningitidis by PCR [10] |
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| N. meningitidis by antigen test only [3] |
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* Numbers of patients in brackets # 5 patients had contraindications to LP, (all were shocked, and 2 had deep come): 2 with BC, and 1 with PCR positive for N meningitidis BC = blood cultures, CSF = cerebrospinal fluid, WBC = white blood cells PCR was only performed on blood | ||||
Kneen et al. BMC Pediatrics 2002 2:8 doi:10.1186/1471-2431-2-8 |
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