Table 6

Short-term neurological outcomes
Outcome Whole cohort n = 60 (100%) Thompson < 7 n = 16 (100%) Thompson ≥ 7 n = 44 (100%)
Mild encephalopathy a 12 (20) 11 (69) 1 (2) *
Moderate encephalopathy a 27 (45) 5 (31) 22 (50) *
Severe encephalopathy a 21 (35) 0 21 (48) *
aEEG or Clinical Seizure 35 (58) 0 35 (80) *
Mean core temperature age 3 hours (±SD) 35.3 (±1.1) 36.3 (±0.4) 34.9 (±1.0) *
aEEG normal at 6 and 24 hours 23 (38) 16 (100) 7 (16) *
aEEG abnormal age 3 hours (n=50) 33 (66) 2(13) 31(71) *
aEEG abnormal age 6 hours 36 (60) 0 36 (82) *
aEEG abnormal age 3 or 6 hours 40 (67) 2(13) 38 (86) *
aEEG severely abnormal age 6 hours 25 (42) 0 25 (57) *
aEEG severely abnormal age 24 hours 18 (30) 0 18 (41) **
Dead or aEEG severely abnormal age 48 hours 12 (20) 0 12 (27)
Maximum Thompson score ≥ 15 21 (35) 0 21 (48) **
Dead or maximum Thompson Score ≥ 15 22 (37) 0 22 (50) *
Dead 8 (13) 0 8 (19)
Median age at death, d (Range) (n=8) 2 (1.5 – 5) - 2 (1.5 – 5)
Thompson score normal (0) by day 7 22 (42) 13 (81) 9 (25) *

LOC: Level of consciousness, aEEG: amplitude-integrated EEG.

a: Highest modified Sarnat encephalopathy grade recorded in the first 72 hours.

* p<0.0001, ** p=0.001, † p=0.025, ‡ p=0.09.

Horn et al.

Horn et al. BMC Pediatrics 2013 13:52   doi:10.1186/1471-2431-13-52

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