Table 1

Characteristics of the ELBW infants in this study
Group 1 Group 2 Group 3 p-value*
(1997–2000) (2001–2005) (2006–2009)
(N = 65) (N = 178) (N = 172)
Gestational age (w) 27.0 (26–28) 27.0 (25.6-29.0) 26.9 (25.7-28.8) 0.988
Birth weight (g) 814 (680–935) 800 (700–915) 800 (700–900) 0.903
IUGR 24 (38.1%) 63 (36.0%) 62 (39.0%) 0.773
Multiple gestation 21 (32.3%) 60 (33.7%) 69 (40.1%) 0.180
Male gender 26 (40%) 92 (51.7%) 80 (46.5%) 0.684
Chorioamnionitis 5 (7.7%) 31 (17.4%) 45 (26.2%) 0.004
Antibiotics (mother) 40 (62.5%) 104 (62.3%) 101 (62.7%) 0.956
Prenatal steroids 52 (81.3%) 165 (96.5%) 157 (91.8%) 0.097
Cesarean section 44 (67.7%) 121 (68.8%) 101 (59.1%) 0.098
Apgar at 1 min ≤3 19 (30.2%) 26 (14.6%) 21 (12.3%) 0.004
Apgar at 5 min ≤6 11 (16.9%) 25 (14.3%) 25 (15.2%) 0.836
Umbilical artery pH 7.23 (7.13-7.30) 7.27 (7.21-7.32) 7.27 (7.17-7.32) 0.019
- Not 9performed 9 (13.8%) 39 (21.9%) 25 (14.5%) 0.133
- Mask/IPPV + PEEP 6 (9.2%) 65 (36.5%) 70 (40.7%) <0.001
- ETI 44 (67.7%) 67 (37.6%) 70 (40.7%) <0.001
- ETI + ChC + E 6 (9.2%) 7 (3.9%) 7 (4.1%) 0.195
- ET intubation 56 (86.2%) 121 (68.0%) 123 (71.5%) 0.143
- Duration (days) 4 (1–9) 2 (0–5) 2 (0–7) 0.005

IUGR: intrauterine growth restriction; ETI: endotracheal intubation; ChC: chest compression; E: epinephrine; IPPV: intermittent positive pressure ventilation; PEEP: positive end-expiratory pressure.

Median (IQR: 25th-75th percentile), number (%).

Kruskal-Wallis or chi-square test.

Botet et al.

Botet et al. BMC Pediatrics 2012 12:63   doi:10.1186/1471-2431-12-63

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