Table 2

Comparison of CPT1A P479L homozygosity in unexpected infant death cases (SIDS, SUDI and infection) occurring in Nunavut (July 1, 1999-June 30, 2011) to the estimated population P479L homozygosity [24], by region and territory
Cases Population Odds Ratio (95%CI) 2 sided FETp
n f (95%CI) n f (95%CI)
NUNAVUT 30 85.7 (69.7-95.2) 442 63.6 (59.9-67.2)* 3.43 (1.30-11.47) 0.006
 Qikiqtani 8 88.9 (51.8-99.7) 162 53.6 (47.8-59.4)* 6.91 (0.90- 308.87) 0.044
 Kivalliq 16 88.9 (62.5-98.6) 170 70.0 (63.8-75.7) 3.44 (0.77-31.45) 0.108
 Kitikmeot 6 75.0 (34.9-96.8) 110 73.3 (65.5-80.2) 1.09 (0.19-11.47) 1.000
 Kivalliq & Kitikmeot (combined) 22 84.6 (65.1-95.6) 290 71.2 (66.5-75.7) 2.22 (0.73-9.04) 0.178

* Genotype frequencies deviated from Hardy-Weinberg equilibrium (p<0.05) [24].

f = frequency. CI = confidence interval. FET = fisher’s exact test.

Collins et al.

Collins et al. BMC Pediatrics 2012 12:190   doi:10.1186/1471-2431-12-190

Open Data