Table 2

Association between mode of delivery and asthma and allergy outcomes at age 8–9 years
Outcomes Total Population Prevalence (95% CI) Odds ratios by mode of delivery (Born by C/S Vs vaginally)
Born vaginally Born by C/S Unadjusted OR (95% CI), p-value Adjusted OR† (95% CI), p-value
Whole sample* n=2216 n= 1500 n= 695
Ever Wheeze 25.0 23.1 29.5 1.38 (1.13-1.69), 1.36 (1.07- 1.71)
(23.2-26.8) (21.0-25.2) (26.1-32.9)
Current Wheeze 8.6 7.5 11.1 1.53 (1.13-2.08) 1.23 (0.87- 1.74)
(7.4-9.8) (6.2-8.8) (8.8-13.4)
Ever Asthma 17.6 15.9 21.3 1.44 (1.14-1.80) 1.41 (1.09- 1.83)
(16.0-19.2) (14.0-17.8) (18.3-24.3)
Active Asthma 5.7 5.1 7.2 1.44 (1.00-2.08) 1.23 (0.81- 1.88)
(4.7-6.7) (4.0-6.2) (5.3-9.1)
Sub-group* n=746 n= 507 n= 354
Atopic Sensitization 15.1 13.7 18.5 1.47 (0.98- 2.20) 1.67 (1.08- 2.60)
(12.6-17.6) (10.8-16.6) (13.7-23.3)

† Adjusted for sex, country of birth, district, urban/rural residence, birth order, parental level of education, parental smoking at home, mother smoking during pregnancy, exclusive breastfeeding for more than 2 months, birth weight <2500 gr., nursery attendance in the first year of life, bedroom sharing with older sibling, and family history of allergy. * Numbers reflect missing values on some variables.

Kolokotroni et al.

Kolokotroni et al. BMC Pediatrics 2012 12:179   doi:10.1186/1471-2431-12-179

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