Table 2

Details of microbiology results and management in 10 children with a confirmed diagnosis of CNS infection
Final diagnosis CSF WCC cells/ml CSF glucose mmol/L (CSF/plasma ratio) CSF PCR Blood cultures Treatment Duration (days) Microbiology/ID advice sought?
Aseptic Meningitis 8 4.5 (no plasma glucose) Negative Negative cephalosporin 4 Yes
28 3.9 (no plasma glucose) Negative Escherichia coli cephalosporin 3 Yes
20 2.9 (no plasma glucose) Not done Negative cephalosporin 2 Yes
130 3.7 (0.62) Not done Negative cephalosporin 21 Yes
Purulent Meningitis Blood stained Blood stained Not done Haemophillus influenzae type b cephalosporin 9 Yes
aciclovir 1
632 4.7 (0.76) Negative Group B Neisseria meningitidis cephalosporin 12 Yes
112 0.17 (0.03) Negative Negative cephalosporin 7 Yes
Encephalitis 0 2.7 (0.44) Adeno virus species Negative aciclovir 8 No
cephalosporin 8
0 5.2 (no plasma glucose) Herpes Simplex Virus 1 Negative aciclovir 7 No
cephalosporin 7
7.2 (lymphocytosis) 3.6 (0.56) Herpes Simplex Virus 1 Negative aciclovir 14 Yes
cephalosporin 2

Kelly et al.

Kelly et al. BMC Pediatrics 2012 12:145   doi:10.1186/1471-2431-12-145

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