Table 5

Placental findings associated with gastroschisis

Placental findings

Controls N = 29

Gastroschisis N = 31

p-value


Placental weight z-score (mean ± sd)a

0.24 ± 1.29

-0.03 ± 1.07

0.804b

Chorioamnionitis (%)

14 (48)

13 (42)

0.796c

Any chorangiosis (%)d

12 (41)

25 (81)

0.003c

Focal chorangiosis (%)d

8 (28)

12 (39)

0.419c

Diffuse chorangiosis (%)e

4 (14)

13 (42)

0.022c


a Excludes the placentas of patients who were SGA (n = 9), had hydrops (n = 5), or both (n = 3).

b Rank-sum test

c Fisher exact test

d Focal chorangiosis was defined as ≥ 10 capillaries in ≥ 10 terminal villi in 10 fields at 10× magnification in each of 1-2 areas (slides).

e Diffuse chorangiosis was defined as ≥ 10 capillaries in ≥ 10 terminal villi in 10 fields at 10× magnification in each of 3 areas (slides).

Payne et al. BMC Pediatrics 2011 11:90   doi:10.1186/1471-2431-11-90

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