Table 2

Daily flow chart summarising PN administration (maximum possible) and data collection

PN administration (macronutrient content)

Week

Data collection (nutrition)


Age (d)

Protein (g)

Lipid (g)

Dextrose; PN (%)

Dextrose; Suppl (%)

1

Enteral/IV fluid intake (ICR)

U/EBG

Bone/LFT

TG

AA

Growth


std

max

std

max

std

max

std

max

PN type


1

1.8

1.8

1.0

1.0

10

10

10

10

PN


2

1.8

1.8

1.0

1.0

10

10

10

10

Consent &


3

2.4

2.9

1.9

1.9

10

12

10

12

randomise


4

2.4

2.9

1.9

1.9

10

12

10

12


5

2.8

3.8

2.8

2.8

10

12

10

12


6

2.8

3.8

2.8

2.8

10

12

10

12

SCAMP


7

2.8

3.8

2.8

3.8

10

12

10

12

SCAMP


PN administration (macronutrient content)

Week

Data collection (nutrition)


Age (d)

Protein (g)

Lipid (g)

Dextrose; PN (%)

Dextrose; Suppl (%)

2-4

Enteral/IV fluid intake (ICR)

U/EBG

Bone/LFT

TG

AA

Growth


std

max

std

max

std

max

std

max

PN type


8

2.8

3.8

2.8

3.8

10

12

10

12

SCAMP


9

2.8

3.8

2.8

3.8

10

12

10

12

SCAMP


10

2.8

3.8

2.8

3.8

10

12

10

12

SCAMP


11

2.8

3.8

2.8

3.8

10

12

10

12

SCAMP


12

2.8

3.8

2.8

3.8

10

12

10

12

SCAMP


13

2.8

3.8

2.8

3.8

10

12

10

12

SCAMP


14

2.8

3.8

2.8

3.8

10

12

10

12

SCAMP


Legend: Daily flow chart summary of SCAMP nutrition study protocol including consent, randomisation, PN administration and data collection. Week 2 flow chart is repeated in week 3 and 4 to complete the 28 day intervention period. Day 29: Patient reverts to standard PN (if still on PN). All routine data collection stops apart from routine weekly growth data which continues until 36 weeks corrected for gestational age.

Abbreviations: stnd: standard PN (scNPN); max: scNPNmax; ICR: intensive care record of daily fluid/nutrient/drug administration; U/E, BG: routine biochemical monitoring of plasma electrolytes, glucose, lactate and blood gases; Bone/LFT: routine biochemical monitoring of plasma bone and liver biochemistry; TG: triglyceride levels; AA amino acid levels.

Morgan et al. BMC Pediatrics 2011 11:53   doi:10.1186/1471-2431-11-53

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