Table 5

Medical Characteristics by Seizure Group.

Medical Diagnosis

Overall

Control

Clinical Seizures

Subclinical Seizures


Prematurity

15%

13%

15% ns

16% ns,ns


Cerebral Palsy

4%

1%

5% ns

3% ns,ns


Sensory Integration Disorder

51%

53%

48% ns

58% ns,ns


ADHD

31%

31%

30% ns

31% ns,ns


Hypotonia

24%

20%

26% ns

27% ns,ns


Mental Retardation

20%

7%

28%

18% ns,ns


Mitochondrial disorder

10%

6%

11% ns

17% ns,ns


Genetic Disorder

6%

4%

7% ns

7% ns,ns


Renal disease

2%

2%

2% ns

1% ns,ns


Cardiovascular disease

2%

2%

2% ns

2% ns,ns


Hematological disease

1%

1%

1% ns

1% ns,ns


Growth


Failure-to-Thrive

14%

11%

14% ns

15% ns,ns


Macrocephaly

11%

9%

11% ns

13% ns,ns


Accelerated Growth

10%

11%

9% ns

9% ns,ns


Microcephaly

4%

4%

4% ns

3% ns,ns


Gastrointestinal Disorders


Constipation

41%

39%

42% ns

40% ns,ns


GERD

22%

22%

22% ns

25% ns,ns


Inflammation

17%

12%

18% ns

24% ns,ns


Dysbiosis

16%

12%

16% ns

22% ns,ns


LNH

4%

2%

4% ns

7% ns,ns


Sleep Disorders


Disrupted Sleep

44%

34%

47% ns

53% ns,ns


Insomnia

22%

27%

34% ns

33% ns,ns


Apnea

9%

8%

9% ns

9% ns,ns


PLMS

6%

5%

6% ns

9% ns,ns


†p < = 0.0001

For each characteristic listed, statistical comparisons were made between the clinical seizure group and the control group (superscript after the clinical seizure percentage), the subclinical seizure group and the control group (1st superscript after the subclinical seizure percentage) and between the clinical and subclinical seizure group (2nd superscript after the subclinical seizure percentage). There are 24 medical diagnoses and 3 comparisons for each medical diagnosis resulting in 72 comparisons. The Bonferroni correction results in an alpha of 0.05/72 = 0.0007, so we have set the alpha to p < = 0.0001 to be conservative.

Frye et al. BMC Pediatrics 2011 11:37   doi:10.1186/1471-2431-11-37

Open Data