Table 7

ATP/NADH/NADPH/Co-Q10.

Units

Neuro-typicals

(n = 44)

Arizona Treatment Group

(n = 18)

Arizona Placebo Group

(n = 22)


Pre

Post

% change

p-value

Pre

Post

% change

p-value


ATP

(plasma)

nmol/l

18.5

+/- 4.7

15.5

+/- 3.7

19.3

+/- 2.3

+25%

0.00001

14.0

+/- 4.9

15.6

+/- 3.7

+11%

0.08


NADH

(RBC)

nmol/ml

20.7

+/- 4.3

15.7

+/- 4.5

20.1

+/- 5.1

+28%

.00002

15.3

+/- 3.9

16.4

+/- 4.1

+8%

0.06


NADPH

(RBC)

nmol/ml

30.9

+/- 8.5

23.0

+/- 7.7

29.9

+/- 7.1

+30%

0.001

21.9

+/- 5.3

23.9

+/- 7.2

+9%

n.s.


CoQ10

(plasma)

ug/ml

0.60

+/- 0.16

0.56

+/- 0.14

1.41

+/- 0.58

+153%

0.00001

0.57

+/- 0.18

0.71

+/- 0.26

+26%

0.01


The average levels of biomarkers measured in the Neurotypical group and the Autism Treatment and Autism Placebo groups (pre and post) who completed the study are reported below, along with their standard deviations. The p-value for a t-test comparison of the change in the level is reported. If the p-value is below 0.05, then the result is highlighted.

Adams et al. BMC Pediatrics 2011 11:111   doi:10.1186/1471-2431-11-111

Open Data