Table 7 

ATP/NADH/NADPH/CoQ10. 

Units 
Neurotypicals (n = 44) 
Arizona Treatment Group (n = 18) 
Arizona Placebo Group (n = 22) 



Pre 
Post 
% change 
pvalue 
Pre 
Post 
% change 
pvalue 



ATP (plasma) 
nmol/l 
18.5 +/ 4.7 
15.5 +/ 3.7 
19.3 +/ 2.3 
+25% 
0.00001 
14.0 +/ 4.9 
15.6 +/ 3.7 
+11% 
0.08 


NADH (RBC) 
nmol/ml 
20.7 +/ 4.3 
15.7 +/ 4.5 
20.1 +/ 5.1 
+28% 
.00002 
15.3 +/ 3.9 
16.4 +/ 4.1 
+8% 
0.06 


NADPH (RBC) 
nmol/ml 
30.9 +/ 8.5 
23.0 +/ 7.7 
29.9 +/ 7.1 
+30% 
0.001 
21.9 +/ 5.3 
23.9 +/ 7.2 
+9% 
n.s. 


CoQ10 (plasma) 
ug/ml 
0.60 +/ 0.16 
0.56 +/ 0.14 
1.41 +/ 0.58 
+153% 
0.00001 
0.57 +/ 0.18 
0.71 +/ 0.26 
+26% 
0.01 


The average levels of biomarkers measured in the Neurotypical group and the Autism Treatment and Autism Placebo groups (pre and post) who completed the study are reported below, along with their standard deviations. The pvalue for a ttest comparison of the change in the level is reported. If the pvalue is below 0.05, then the result is highlighted. 

Adams et al. BMC Pediatrics 2011 11:111 doi:10.1186/1471243111111 