Figure 4.

Corneal thickness measurements from 1-year monkey studies. (A) Effect of topical administration of latanoprost vehicle containing 0.2 mg/mL (0.02%) benzalkonium chloride on corneal thickness in monkeys. p > 0.4 for vehicle-treated versus untreated eyes in both male and female monkeys at all time points. PD = predose. (B) Effect of the topical administration of suprapharmacologic doses of latanoprost (100 μg/day) on corneal thickness in monkeys. p > 0.5 for the vehicle-treated versus latanoprost-treated eyes in both male and female monkeys at all time points. PD = predose.