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Open Access Research article

Effect of fibrin glue as an adjuvant to hang-back surgery

Jihyun Park1, Jung Jin Lee1, Eun Hye Lim1, Joon H Lee2, Kyung Hyun Jin3 and Ungsoo Samuel Kim4*

Author Affiliations

1 Department of Ophthalmology, Kim’s Eye Hospital, Konyang University College of Medicine, Seoul, South Korea

2 Myung-Gok Eye Research Institute, Konyang University College of Medicine, Seoul, South Korea

3 Department of Ophthalmology, KyungHee University School of Medicine, Seoul, South Korea

4 Department of Ophthalmology, Postgraduate School, Kyung Hee University, Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea

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BMC Ophthalmology 2012, 12:14  doi:10.1186/1471-2415-12-14

Published: 7 June 2012

Abstract

Background

The hang-back surgery is a useful technique in the field of strabismus surgery. The aim of this study is to determine the stabilizing effects of fibrin glue as an adjuvant to hang-back surgery.

Materials and methods

Four (4)-mm hang-back recessions of the superior rectus muscle was performed in 32 eyes of 16 rabbits. Only in the left eye of the 16 rabbits, fibrin glue was applied between the recessed muscle bed and the sclera at the end of hang-back surgery (fibrin glue group). After 6 weeks, we compared the stability of the recessed rectus muscle between the fibrin glue group and the control group by evaluating the displacement of the muscle.

Results

The frequency of stable insertion of the recessed muscle at the intended site was greater in the fibrin glue group (9 eyes) compared to the control group (3 eyes) (p = 0.028). In the control group, 5 eyes showed anterior displacement and 8 eyes showed posterior displacement and in the fibrin glue group, 1 eye showed anterior displacement, and 6 eyes showed posterior displacement. Anterior displacement was more common in the control group (6.3% Vs 31.3%). The control group and the fibrin glue group showed similar histological findings on microscopic examination.

Conclusions

Fibrin glue is effective in stabilizing the new rectus muscle insertion and decreasing the displacement in the hang-back surgery.

Keywords:
Fibrin glue; Hang-back surgery; Rabbit