Table 3

Summary Results from the Meta-analysis

RISK FACTOR

PROSPECTIVE

CROSS-SECTIONAL

CASE CONTROL


n

Overall estimate

n

Overall estimate

n

Overall estimate


Gender (female)

2

1.01 (0.89 - 1.16)

2

1.06 (0.78 - 1.44)

2

1.00 (0.83 - 1.21)


Race (white vs. other)

3

0.91 (0.49 - 1.69)

3

1.09 (0.09 - 13.56)*

1

4.2 (2.23 - 8.00)


Family History*

0

1

3.95 (1.35 - 11.54)

2

6.18 (0.98 - 38.90)*


Cataract surgery*

4

3.05 (2.05 - 4.55)

2

1.59 (1.08 - 2.34)

3

1.54 (1.24 - 1.91)


Iris colour*

5

0.98 (0.72 - 1.32)

4

0.88 (0.65 - 1.17)

2

0.60 (0.12 - 2.98)*


Body Mass Index*

9

1.28 (0.98 - 1.67)*

10

1.21 (0.97 - 1.53)

2

1.52 (1.15 - 2.00)


Smoking*

5

1.86 (1.27 - 2.73)

7

3.58 (2.68 - 4.79)

6

1.78 (1.52 - 2.09)


Hypertension*

4

1.02 (0.77 - 1.35)

6

1.15 (0.88 - 1.51)

3

1.48 (1.22 - 1.78)


Diabetes*

3

1.66 (1.05 - 2.63)

3

1.09 (0.61 - 1.92)

1

0.55 (0.06 - 4.87)


Cardiovascular Disease*

7

1.22 (0.92 - 1.63)

9

1.12 (0.86 - 1.47)

6

2.20 (1.49 - 3.26)*


Cerebrovascular Diseases

2

1.54 (0.82 - 2.90)

5

1.10 (0.69 - 1.75)

0


Serum Cholesterol (Total)

4

0.99 (0.95 - 1.03)

5

0.94 (0.84 - 1.04)

1

4.66 (1.35 - 16.11)


Serum Cholesterol (HDL)

3

1.00 (0.97 - 1.02)

5

1.06 (0.80 - 1.39)

1

3.35 (0.92 - 12.23)


Serum Triglycerides

2

1.00 (0.77 - 1.30)

3

1.08 (0.89 - 1.30)

1

0.90 (0.25 - 3.24)


Plasma Fibrinogen*

1

1.03 (0.81 - 1.32)

3

1.45 (1.22 - 1.73)

0


n = number of estimates entered in the models; *Figure is displayed

* Estimates from random effects models. All other estimates are fixed effects.

Chakravarthy et al. BMC Ophthalmology 2010 10:31   doi:10.1186/1471-2415-10-31

Open Data