Table 1

3D matrix induced morphology measurements; EFF ┬▒

substrate

2D

control 3D

tumor-associated 3D

treatment

Ctrl

Ctrl

Wt 10 nM

Wt 50 nM

mAb13

mAb13 +Wt 10 nM

mAb13 +Wt 50 nM

Ctrl

Wt 10 nM

Wt 50 nM

mAb13

mAb13 +Wt 10 nM

mAb13 +Wt 50 nM


Median (mEFF)

1.5

1.7

1.5

1.4

1.4

1.3

1.3

2.2

2.3

1.6

1.4

1.4

1.3


Sample Size

172

251

192

294

173

130

221

292

210

290

206

181

248


Std. Err

0.1

0.1

0.1

0.1

0.1

0.1

0.0

0.1

0.1

0.1

0.1

0.1

0.0


┬▒EFF = elliptical form factor ratio.

Castell├│-Cros et al. BMC Cancer 2009 9:94   doi:10.1186/1471-2407-9-94

Open Data