Additional file 6.
Invasive cell motility through staged 3D ECMs under PI3K and/or beta-1 integrin inhibition. Montage of six hour time-lapse videos depicting MDA-MB-231 cells within 3D control (bottom panels) or tumor-associated (top panels) matrices, in the presence of 50 nM Wortmannin alone (left panels) or in combination with 50 μg/ml mAb13 (right panels).
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Castelló-Cros et al. BMC Cancer 2009 9:94 doi:10.1186/1471-2407-9-94