Figure 4.

Perforated block in the stroma: multiple rounds. The Initial State represents stable tissue architecture when a solid block is first inserted into the stroma. A round is one cycle of cell movement and morphostat update through all the cells. At Round 5 scattered aberrant cells form above top layer cells, which persists through later rounds.

Baker et al. BMC Cancer 2009 9:89   doi:10.1186/1471-2407-9-89
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