Table 1

Deleterious mutations identified among fifty-four triple-negative cases:

Gene

Exon

Mutation

Mutation Type

Age of Onset

Ethnic Group


BRCA1

11

1294del40

Deletion

35

Caucasian

BRCA1

11

2800delA

Deletion

32

Irish/Scottish

BRCA1

15

4731C>T

Nonsense

36

Caucasian

BRCA1

20

5382insC

Insertion

38

Caucasian

BRCA1

20

5382insC

Insertion

39

Caucasian

BRCA2

11

4936delAG

Deletion

39

African American


Young et al. BMC Cancer 2009 9:86   doi:10.1186/1471-2407-9-86

Open Data