Figure 4.

Immunohistochemical staining of CD105 in salivary gland tumors (streptavidin-biotin-peroxidase technique, original magnification = × 250). A. Pleomorphic adenoma, depicting very weak staining (arrow). B. Only one primary non metastasizing adenoid cystic carcinoma was positive for CD105 staining, of weak intensity (arrow). C. Adenoid cystic carcinoma, primary metastasizing lesion, depicting clear and strong positivity around and within tumoral nests (arrows). D. Polymorphous low-grade adenocarcinoma, primary non-metastasizing lesion, with strongly positive vessels (arrow) permeating tumoral strands. E. Mucoepidermoid carcinoma, primary non-metastasizing lesion, with strongly positive vessels (arrows) around tumoral nests. F. Mucoepidermoid carcinoma, primary metastasizing lesion, evidencing numerous and strongly positive vessels (arrows) intermingling tumoral parenchima.