Open Access Highly Accessed Research article

Expression profiling identifies genes involved in neoplastic transformation of serous ovarian cancer

Melissa A Merritt13, Peter G Parsons1, Tanya R Newton1, Adam C Martyn1, Penelope M Webb2, Adèle C Green2, David J Papadimos4 and Glen M Boyle1*

Author Affiliations

1 Division of Cancer and Cell Biology, Queensland Institute of Medical Research, Brisbane, Queensland, Australia

2 Division of Genetics and Population Health, Queensland Institute of Medical Research, Brisbane, Queensland, Australia

3 School of Population Health, University of Queensland, Brisbane, Queensland, Australia

4 Sullivan Nicolaides Pathology Laboratory, Brisbane, Queensland, Australia

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BMC Cancer 2009, 9:378  doi:10.1186/1471-2407-9-378

Published: 23 October 2009

Additional files

Additional file 1:

Tissues analysed by oligonucleotide microarray. Detailed descriptions of normal and tumor tissues analyzed by microarray analysis.

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Additional file 2:

Validation set tissues analysed by real time PCR. Detailed descriptions of normal and tumor tissues analyzed by quantitative real time PCR analysis.

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Additional file 3:

Genes identified by ANOVA analysis of oligonucleotide microarray data. Full gene list detailing comparisons of serous tumors (benign, LMP, invasive) vs normal ovaries.

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Additional file 4:

Genes differentially expressed between serous invasive and benign tumors. Full gene list detailing comparisons of serous invasive vs benign tumors.

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Additional file 5:

Genes differentially expressed between serous invasive and normal ovarian tissue. Full gene list detailing comparisons of serous invasive vs normal whole ovaries.

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Additional file 6:

Representative images of tissues used in the study. H+E staining of representative tissues that were included as part of the study.

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Additional file 7:

WNT pathway and related molecules expression profiling data. Expression profiling data of all WNT pathway and related molecules present on the microarrays.

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