Table 5

Comparison of individual and overall (random-effects) estimates for the two reviews – lung cancer

ST usea


Ref

Type

Exposure

Inclusion of smokersb

Reviewc

Sex

Relative risk (95% CI)

Comments


[31]

ST

Ever

NS

L&H

F

6.80 (1.60–28.5)

Not included by B

[3]

ST

Current

NS

L&H

M

1.08 (0.64–1.83)

(CPS-I)

ST

Current

NS

B

M

1.1 (0.6–1.8)

Estimates agreed

[3]

ST

Ever

NS

L&H

M

1.77 (1.14–2.74)e

(CPS-II)

ST

Current

NS

B

M

2.0 (1.2–3.2)

Current not ever exposure

[4]

Snuff

Ever

SNS

L&H

M

0.80 (0.61–1.05)

Estimate for NS also available

Snuff

Ever

SNS

B

M

0.8 (0.6–1.1)

Estimates agreed

[5]

Snuff

Ever

SNS

L&H

M

0.7 (0.6–0.7)

Snuff

Ever

NS

B

M

0.8 (0.5–1.3)

NS not SNS

[27]

ST

Ever

SNS

L&H

M

0.69 (0.47–1.00)e

Not included by B

Total

L&H

0.99 (0.71–1.37)

6 estimates

B

1.2 (0.7–1.9)

5 estimatesf


a ST = smokeless tobacco; ever exposure includes undefined use.

b NS = never smokers; SNS = smokers and nonsmokers combined (with adjustment for smoking).

c L&H = Lee and Hamling review [2]; B = Boffetta et al. review [1].

d To within rounding error, as B only expressed estimates to one decimal place.

e Estimated from data provided.

f B only presented four estimates, but a combined result stated to be based on five. The random-effects estimate for the four estimates provided is 1.1 (0.7–1.6)

Lee and Hamling BMC Cancer 2009 9:256   doi:10.1186/1471-2407-9-256

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