Table 1 |
|||
|
Patient Characteristics |
|||
|
All patients (N = 16) |
Low risk group (CXCR4 ≤ 2500 cells/ml) (n = 11) |
High risk group (CXCR4 > 2500 cells/ml) (n = 5) |
|
|
|
|||
|
Gender |
|||
|
F |
8 |
5 |
3 |
|
M |
8 |
6 |
2 |
|
Age |
|||
|
Mean ± SD |
69 ± 10 |
67 ± 11 |
74 ± 6 |
|
Min-max, median |
42–83, 73 |
42–79, 70 |
67–83, 73 |
|
Stage |
|||
|
IA |
2 |
2 |
0 |
|
IIIA |
1 |
0 |
1 |
|
IIIB |
1 |
1 |
0 |
|
IV |
12 |
8 |
4 |
|
ECOG PS |
|||
|
0 |
10 |
7 |
3 |
|
1 |
6 |
4 |
2 |
|
Histology |
|||
|
Adenocarcinoma |
6 |
4 |
2 |
|
Large cell |
1 |
0 |
1 |
|
Squamous cell |
2 |
1 |
1 |
|
Not Specified |
7 |
6 |
1 |
|
Tobacco (pack-years) |
|||
|
0 |
2 |
2 |
0 |
|
1–20 |
4 |
3 |
1 |
|
>20 |
10 |
6 |
4 |
|
# of prior treatments |
|||
|
0 |
14 |
9 |
5 |
|
1 |
2 |
2 |
0 |
|
Mean Survival (weeks) |
65 ± 50 |
79 ± 46 |
34 ± 50 |
|
Median Survival (weeks) |
60 (6-NA) |
NA (15-NA) |
14 (6-NA)* |
|
|
|||
|
NA, not achieved *p = 0.03 and hazard ratio of 0.23 (95% CI, 0.02–0.79) for median survival of low risk group versus high risk group (log-rank test). |
|||
|
Reckamp et al. BMC Cancer 2009 9:213 doi:10.1186/1471-2407-9-213 |
|||
