Research article
Chromosomal imbalance in the progression of high-risk non-muscle invasive bladder cancer
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* Corresponding author: Karsten Zieger karsten.zieger@ki.au.dk
1 Department of Molecular Medicine, Aarhus University Hospital Skejby, Aarhus N, Denmark
2 Department of Urology, Aarhus University Hospital Skejby, Aarhus N, Denmark
3 Bioinformatics Research Center, Aarhus University, Aarhus, Denmark
BMC Cancer 2009, 9:149 doi:10.1186/1471-2407-9-149
Published: 16 May 2009Additional files
Additional file 1:
Clinical data of the patients in the study. Including age and gender, stage and grade of the primary and (if different) analysed tumors, supplementary treatment (BCG), CIS-status, length of follow-up/progression-free survival, causes of death and overall survival.
Format: XLS Size: 46KB Download file
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Additional file 2:
Genome-wide copy number differences, 50 K+10 K data (6.4 K resolution). Graphical illustration of genome-wide copy number differences between tumors with and with no subsequent progression. Compiled results of all SNP microarray data (n = 46) with a resolution of 6.4 K SNPs.
Format: PDF Size: 813KB Download file
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Additional file 3:
Genome-wide differences in probability of LOH, 50 K+10 K data. Graphical illustration of genome-wide differences in probability of LOH between tumors with and with no subsequent progression. Compiled results of all SNP microarray data (n = 47).
Format: PDF Size: 630KB Download file
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Additional file 4:
Genome-wide copy number differences, 50 K data only (41 K resolution). Graphical illustration of genome-wide copy number differences between tumors with and with no subsequent progression. 50 K SNP microarray data only (n = 29).
Format: PDF Size: 867KB Download file
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Additional file 5:
Genome-wide differences in probability of LOH, 50 K data only. Graphical illustration of genome-wide differences in probability of LOH between tumors with and with no subsequent progression. 50 K SNP microarray data only (n = 28).
Format: PDF Size: 650KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 6:
Selected gene loci, primer sequences and genomic annotation of the amplicons used for QPCR validation.
Format: DOC Size: 51KB Download file
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Additional file 7:
Chromosomal imbalance of the analysed tumors. Contains detailed data of the fractions of the genome altered (FGA), specified separately for copy number and LOH changes, as well as the number of QPCR copy number alterations
Format: XLS Size: 41KB Download file
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