Group classifications coupled with response data based on the 180-gene GEPR to EGFR-targeted therapy. Patient populations from Khambata-Ford et al were classified using our predictive model. Percentage of patients exhibiting each annotated radiographic responses (CR/PR – complete responses and partial responses, SD – stable disease, PD – progressive disease, NA – not available/not reported) are classified as 'sensitive' or 'resistant' groups. A: KRAS-wildtype patients (43 subjects); B: all patients (80 subjects); and C: KRAS-mutant patients (27 subjects).
Balko and Black BMC Cancer 2009 9:145 doi:10.1186/1471-2407-9-145