Table 4 |
||||
|
Prognostic impact (PI) of different tumor- and patient-related parameters |
||||
|
n |
PI of hormone receptor status |
PI of HER-2 status |
PI of various factors (multivariate) |
|
|
|
||||
|
Claude et al. [10] |
120 |
none |
no data |
performance status, lymphopenia |
|
Bartsch et al. [16] |
174 |
none |
none |
performance status, number of metast. sites |
|
Le Scodan et al. [11] |
117 |
receptor negative sign. worse |
none |
performance status, lymphopenia, hormone receptor status |
|
Nam et al. [17] |
126 |
receptor negative sign. worse |
HER-2 negative sign. worse |
number of metast. sites, age, hormone and HER-2 receptor status, leptomeningeal disease |
|
Eichler et al. [18] |
83 |
none |
HER-2 negative sign. worse |
HER-2 receptor status, number of brain metast., local disease control |
|
Melisko et al. [19] |
112 |
receptor negative sign. worse |
none |
hormone receptor status, age, performance status, stable or responding systemic disease |
|
Harputluoglu et al. [20] |
144 |
none |
none |
number of brain metast. |
|
Park et al. [21] |
125 |
none |
HER-2 positive sign. worse |
HER-2 receptor status, performance status |
|
Altundag et al. [23] |
420 |
receptor negative sign. worse |
none |
age, hormone receptor status |
|
Wronski et al. [25] |
70 |
receptor negative sign. worse |
no data |
leptomeningeal disease, combined surgery and whole brain radiotherapy |
|
Lee et al. [22] |
198 |
no data |
no data |
performance status, number of brain metast. |
|
Viani et al. [9] |
174 |
no data |
no data |
extracranial metastases, RPA class |
|
Mahmoud-Ahmed et al. [12] |
116 |
no data |
no data |
performance status |
|
Liu et al. [24] |
48 |
no data |
no data |
performance status, number of brain met. |
|
|
||||
|
Nieder et al. BMC Cancer 2009 9:105 doi:10.1186/1471-2407-9-105 |
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