Table 1

Overexpression of HER-2/neu gene and protein in colorectal cancer

Immunohistochemical score

n (%)

FISH amplification

n (%)

0

0 (0)

> 4 signals/cell

0

1+

7 (7)

> 4 signals/cell

0

2+

9 (8)

> 4 signals/cell

1

3+

2 (2)

> 4 signals/cell

2 (2)

HER-2 protein was not over expressed in non-malignant colorectal specimens. The HER-2/neu gene was not over amplified in selected non-malignant specimens.

Kavanagh et al. BMC Cancer 2009 9:1   doi:10.1186/1471-2407-9-1