A) Genome-wide frequency plot of DNA copy number gains (red) and losses (green) for all 30 ESCC tumors. B) Genome-wide copy number profile for a Stage I tumor (ESCC 33). Characteristic alterations for a Stage I tumors are gains on 6p, 12p, and 17p and losses 21q. C) Genome-wide copy number profile for a Stage IV tumor (ESCC 51). Characteristic for Stage IV tumors are gains on 12p, 19q and 20q and frequent losses on 3p, 5q and 9p.
Carneiro et al. BMC Cancer 2008 8:98 doi:10.1186/1471-2407-8-98