|
Correlation of MMP-13 expression with OS of overall and stratified subpopulations. |
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| Tumor |
Stromal Fibroblast |
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|
|
|||||||||
| MMP-13SI |
n |
E |
OS (95% CI) |
p |
n |
E |
OS (95% CI) |
p |
|
|
|
|||||||||
| Overall |
|||||||||
| Low |
133 |
20 |
153 (145~161) |
0.0008 |
132 |
20 |
153(145~161) |
0.0001 |
|
| High |
127 |
47 |
107 (98~116) |
125 |
48 |
106 (97~115) |
|||
| Node Status |
|||||||||
| Negative |
Low |
82 |
8 |
135 (128~142) |
0.3442 |
70 |
6 |
137 (131~143) |
0.1231 |
| High |
43 |
7 |
122 (115~129) |
55 |
10 |
128/(119~137) |
|||
| Positive |
Low |
50 |
12 |
142 (127~158) |
0.0041 |
45 |
13 |
136 (118~153) |
0.0494 |
| High |
82 |
40 |
93 (80~105) |
87 |
39 |
97 (85~108) |
|||
| HER2/neu |
|||||||||
| Negative |
Low |
113 |
14 |
157 (149~165) |
0.0092 |
106 |
15 |
155 (145~163) |
0.0446 |
| High |
93 |
25 |
120 (111~129) |
100 |
25 |
121 (113~130) |
|||
| Positive |
Low |
19 |
6 |
109 (85~133) |
0.0154 |
9 |
4 |
96 (58~133) |
0.5278 |
| High |
32 |
22 |
69 (50~88) |
42 |
24 |
81 (64~98) |
|||
|
OS: Months of overall survival; n: Number of patients; E: Events of positive stains; CI: confidence interval. | |||||||||
Zhang et al. BMC Cancer 2008 8:83 doi:10.1186/1471-2407-8-83 |
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