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Occurrence of tumor growth in prostate and lymph node metastasis of in nude mice treated with alendronate (ALN) or saline (PBS) |
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| Treatment |
Occurrence of tumor growth in prostate (%) |
Occurrence of metastasis in prostate draining lymph nodes (%) |
|
|
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| ALN |
11/15 (73) |
7/11 (64) |
| PBS |
13/16 (81) |
7/13 (54) |
|
Tumors were produced by orthotopic inoculation of 5 × 105 PC-3 cells and tumors were allowed to grow for 4 weeks. | ||
Tuomela et al. BMC Cancer 2008 8:81 doi:10.1186/1471-2407-8-81 |
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