|
Tumor characteristics among 842 unselected breast cancer cases analyzed for NuMA A794G. |
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| NuMA A794G (2381C > G) |
p |
|||
|
|
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| Total |
CC |
CG |
||
| Total |
n = 889 |
837(94.2%) |
52(5.8%) |
|
| Histology |
n = 889 |
ND |
||
| Ductal |
599(71.6%) |
39(75.0%) |
||
| Lobular |
132(15.8%) |
8(15.4%) |
||
| Medullary |
11(1.3%) |
1(1.9%) |
||
| other |
95(11.4%) |
4(7.7%) |
||
| Gradus |
n = 793 |
0.107 |
||
| 1 |
208(27.9%) |
7(14.9%) |
||
| 2 |
316(42.4%) |
26(55.3%) |
||
| 3 |
222(29.8%) |
14(29.8%) |
||
| pT Stage |
n = 801 |
0.767 (Fisher) |
||
| pT1-pT2 |
699(92.6%) |
44(95.7%) |
||
| pT3-pT4 |
56(7.4%) |
2(4.3%) |
||
| Lymph Nodes |
n = 858 |
0.008 |
||
| pN0 |
446(55.3%) |
360(44.7%) |
||
| pN1-2 |
19(36.5%) |
33(63.4%) |
||
| Estrogen Receptor Status |
n = 845 |
0.691 |
||
| Positive |
622(78.4%) |
42(80.8%) |
||
| Negative |
171(21.6%) |
10(19.2%) |
||
| Progesterone Receptor Status |
n = 846 |
0.425 |
||
| Positive |
538(67.8%) |
38(73.1%) |
||
| Negative |
256(32.2%) |
14(26.9%) |
||
| p53 Status |
n = 653 |
0.035 |
||
| Positive |
132(21.3%) |
2(6.1%) |
||
| Negative |
488(78.7%) |
31(93.9%) |
||
| Distant metastasis |
n = 853 |
0.161 (Fisher) |
||
| Positive |
41(5.1%) |
0(0.0%) |
||
| Negative |
765(94.9%) |
47(100.%) |
||
|
The mean age of diagnosis was 57 years for C:C, and 56 for C:G genotypes. | ||||
Kilpivaara et al. BMC Cancer 2008 8:71 doi:10.1186/1471-2407-8-71 |
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