|
Incidence of amenorrhea |
||
| 6FEC 100 |
3FEC/3D |
|
|
|
||
| Amenorrhea at the end of chemotherapy |
78 (93 %) |
65 (92.8 %) |
| Clinically reversible amenorrhea (n = 154) |
||
| Total population** |
20/84 (23.7 %) |
25/70 (35.5 %) |
| Patients < 40 years (39) |
13/18 (72 %) |
15/21 (71.4 %) |
| Patients ≥ 40 years (115)** |
7/66 (10.5 %) |
10/49 (20.5 %) |
| Recovery of premenopausal hormone values * |
||
| Total population (n = 101)** |
18/59 (29 %) |
18/42 (42 %) |
| Patients < 40 years (31) |
11/15 (73.3 %) |
12/16 (75 %) |
| Patients ≥ 40 years (70)** |
6/42 (14 %) |
6/28 (21.4 %) |
| Clinically reversible amenorrhea. No hormone values available (n = 53) |
||
| Patients < 40 years (8) |
2/3 (66 %) |
3/5 (60 %) |
| Patients ≥ 40 years (45)** |
1/24 (4 %) |
4/21 (19 %) |
|
*within a year after the end of chemotherapy ** p < 0.05, chi-square | ||
Berliere et al. BMC Cancer 2008 8:56 doi:10.1186/1471-2407-8-56 |
||