Research article
Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis
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* Corresponding author: Ming-Sound Tsao Ming.Tsao@uhn.on.ca
1 Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada
2 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
3 Department of Biostatistics, Princess Margaret Hospital, Toronto, ON, Canada
4 Department of Medical Oncology, Princess Margaret Hospital, Toronto, ON, Canada
5 Department of Pathology, University Health Network, Toronto, ON, Canada
BMC Cancer 2008, 8:43 doi:10.1186/1471-2407-8-43
Published: 6 February 2008Additional files
Additional file 1:
Additional Figure 1 Tissue microarray. H&E stained TMA and a representative core of negative control staining. Additional Table 1A Summary of Clinical parameters. Identifies surgical procedure, age, sex, tumor stage and grade of patients. Additional Table 1B Clinicopathological parameters of PDAC cases. Sex, age, tumor stage and tumor grade is listed for individual cases.
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Additional file 2:
Additional Table 2 Antibody list. Antibody description, source, method of use and evidence for specificity.
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Additional file 3:
Additional Table 3 Protein levels in PDAC compared with non-neoplastic ductal epithelia. Lists significant associations of high/low protein levels with PDAC specimens compared with duct specimens.
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Additional file 4:
Additional Table 4 Relationships between cytoplasmic and nuclear protein. Lists significant associations in protein levels between cytoplasmic and nuclear compartments.
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Additional file 5:
Additional Table 5 Comparisons of non-neoplastic ducts. Analysis of mean protein levels of non-neoplastic ductal epithelia in peritumoral regions compared with ducts from non-PDAC specimens.
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