|
List of the 60 selected genes |
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| Gene symbols |
Alternate symbols |
Gene name |
Chromosome location |
Genbank accession number |
|
|
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| NFKB genes (n = 11) |
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| NFKB1 |
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) |
4q24 |
NM_003998 |
|
| NFKB2 |
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
10q24 |
NM_002502 |
|
| REL |
v-rel reticuloendotheliosis viral oncogene homolog |
2p13-p12 |
NM_002908 |
|
| RELA |
NFKB3 |
v-rel reticuloendotheliosis viral oncogene homolog A (p65) |
11q13 |
NM_021975 |
| RELB |
v-rel reticuloendotheliosis viral oncogene homolog B |
19q13.32 |
NM_006509 |
|
| CHUK |
IKBKA |
Conserved helix-loop-helix ubiquitous kinase |
10q24-q25 |
NM_001278 |
| IKBKB |
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
8p11.2 |
NM_001556 |
|
| IKBKG |
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma |
Xq28 |
NM_003639 |
|
| NLK |
Nemo like kinase |
17q11.2 |
NM_016231 |
|
| NFKBIA |
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
14q13 |
NM_020529 |
|
| NFKBIB |
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
19q13.1 |
NM_1001716 |
|
| Apoptosis (n = 12) |
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| BCL2A1 |
BFL1/A1 |
Baculoviral IAP repeat-containing 2 |
15q24.3 |
NM_004049 |
| GADD45B |
Growth arrest and DNA-damage-inducible, beta |
19p13.3 |
NM_015675 |
|
| TNFRSF10B |
TRAILR2, DR5 |
Tumor necrosis factor receptor superfamily, member 10b |
8p22-p21 |
NM_003842 |
| FASLG |
FASL, TNFSF6 |
Fas ligand (TNF superfamily, member 6) |
1q23 |
NM_000639 |
| BIRC4 |
XIAP |
Baculoviral IAP repeat-containing 4 |
Xq25 |
NM_001167 |
| TNFAIP3 |
A20 |
Tumor necrosis factor, alpha-induced protein 3 |
6q23 |
NM_006290 |
| TRAF2 |
TNF receptor-associated factor 2 |
9q34 |
NM_021138 |
|
| IER3S |
Immediate early response 3, large transcript |
6p21.3 |
NM_003897 |
|
| IER3L |
Immediate early response 3, short transcript |
6p21.3 |
NM_052815 |
|
| BIRC2 |
c-IAP1 |
Baculoviral IAP repeat-containing 2 |
11q22 |
NM_001166 |
| MCL1S |
Myeloid cell leukemia sequence 1 (BCL2-related), short transcript |
1q21 |
NM_182763 |
|
| MCL1L |
Myeloid cell leukemia sequence 1 (BCL2-related), large transcript |
1q21 |
NM_021960 |
|
| Immune response (n = 15) |
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| IL1A |
Interleukin 1, alpha |
2q14 |
NM_000575 |
|
| IL1B |
Interleukin 1, beta |
2q14 |
NM_000576 |
|
| IL6 |
Interleukin 6 (interferon, beta 2) |
7p21 |
NM_000600 |
|
| IL12B |
Interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) |
5q31.1-q33.1 |
NM_002187 |
|
| IL15 |
Interleukin 15 |
4q31 |
NM_000585 |
|
| CCL2 |
MCP-1 |
Chemokine (C-C motif) ligand 2 |
17q11.2-q21.1 |
NM_002982 |
| CCR5 |
Chemokine (C-C motif) receptor 5 |
3p21 |
NM_000579 |
|
| TNFRSF11A |
RANK |
Tumor necrosis factor receptor superfamily, member 11a, activator of NFKB |
18q22.1 |
NM_003839 |
| TNFSF11 |
RANKL |
Tumor necrosis factor (ligand) superfamily, member 11 |
13q14 |
NM_003701 |
| TNF |
Tumor necrosis factor (TNF superfamily, member 2) |
6p21.3 |
NM_000594 |
|
| IRF7 |
Interferon regulatory factor 7 |
11p15.5 |
NM_001572 |
|
| GBP1 |
Guanylate binding protein 1, interferon-inducible, 67kDa |
1p22.2 |
NM_002053 |
|
| CD40 |
CD40 antigen (TNF receptor superfamily member 5) |
20q12-q13.1 |
NM_001250 |
|
| CD40LG |
CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) |
Xq26 |
NM_000074 |
|
| CD48 |
CD48 molecule |
1q21.3-q22 |
NM_001778 |
|
| Cell Proliferation (n = 8) |
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| CSF1 |
Colony stimulating factor 1 (macrophage) |
1p21-p13 |
NM_000757 |
|
| CSF1R |
Colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog |
5q33-q35 |
NM_005211 |
|
| CSF2 |
Colony stimulating factor 2 (granulocyte-macrophage) |
5q31.1 |
NM_000758 |
|
| CCND1 |
Cyclin D1 (PRAD1: parathyroid adenomatosis 1) |
11q13 |
NM_053056 |
|
| CCND2 |
Cyclin D2 |
12p13 |
NM_001759 |
|
| CCND3 |
Cyclin D3 |
6p21.3 |
NM_001760 |
|
| CCNG1 |
Cyclin G1 |
5q32-q34 |
NM_004060 |
|
| SOD2 |
Mn-SOD |
Superoxide dismutase 2, mitochondrial |
6q25.3 |
NM_000636 |
| Tumor progression (n = 10) |
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| MMP9 |
Matrix metalloproteinase 9 (gelatinase B, 92 kDa type IV collagenase) |
20q11.2-q13.1 |
NM_004994 |
|
| MMP11 |
Matrix metalloproteinase 11 (stromelysin 3) |
22q11.23 |
NM_005931 |
|
| PLAU |
UPA |
Plasminogen activator, urokinase |
10q24 |
NM_002658 |
| CTSB |
Cathepsin B |
8p22 |
NM_001908 |
|
| CXCR4 |
Chemokine (C-X-C motif) receptor 4 |
2q21 |
NM_003467 |
|
| CXCL12 |
SDF1 |
Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) |
10q11.1 |
NM_000609 |
| ICAM1 |
Intercellular adhesion molecule 1 (CD54), human rhinovirus receptor |
19p13.3-p13.2 |
NM_000201 |
|
| VCAM1 |
Vascular cell adhesion molecule 1 |
1p32-p31 |
NM_001078 |
|
| SELE |
ELAM1 |
Selectin E (endothelial adhesion molecule 1) |
1q22-q25 |
NM_000450 |
| TNC |
HXB |
Tenascin C (hexabrachion) |
9q33 |
NM_002160 |
| Angiogenesis (n = 4) |
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| IL8 |
Interleukin 8 |
4q13-q21 |
NM_000584 |
|
| CXCL1 |
GRO1 |
Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
4q21 |
NM_001511 |
| VEGF |
VEGFA |
Vascular endothelial growth factor |
6p12 |
NM_003376 |
| PTGS2 |
COX2 |
Prostaglandin-endoperoxide synthetase 2 |
1q25.2-q25.3 |
NM_000963 |
Lerebours et al. BMC Cancer 2008 8:41 doi:10.1186/1471-2407-8-41 |
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