Table 2

Patient survival in dependence of clinico-pathological parameters and HDAC isoform expression

Parameters

No. of cases

No. of events

Two Year survival time (± SE) in months

p-value

HDAC1 expression

0.285

low

47

12

76.6 (± 6.2)

high

59

10

83.1 (± 4.9)

HDAC2 expression

0.235

low

46

12

76.1 (± 6.3)

high

60

10

83.3 (± 4.8)

HDAC3 expression

0.906

low

92

19

80.5 (± 4.1)

high

14

3

78.6 (± 11.0)

Age

0.119

≤ 61

49

7

85.7 (± 5.0)

>61

57

15

75.4 (± 5.7)

pT stage

<0.001

pT1

53

2

96.2 (± 2.6)

pT2

3

1

66.7 (± 27.2)

pT3

47

17

66.0 (± 6.9)

pT4

3

2

33.3 (± 27.2)

Histological grade

<0.001

G1

11

0

-

G2

74

12

85.1 (± 4.1)

G3

17

7

58.8 (± 11.9)

G4

4

3

25.0 (± 21.7)

pN status

0.001

pN0

50

10

80.0 (± 5.7)

pN1/2

12

8

41.7 (± 14.2)

Metastasis

<0.001

M0

47

5

89.4 (± 4.5)

M1

23

14

43.5 (± 10.3)

Ki-67 index

0.931

≤ 10%

70

15

80.0 (± 4.8)

>10%

36

7

80.6 (± 6.6)

Fritzsche et al. BMC Cancer 2008 8:381   doi:10.1186/1471-2407-8-381