Table 4

Univariate and multivariate analyses of 14-gene signature and Ki-67 LI for distant-metastasis-free survival (DMFS) and overall survival (OS)

Univariate analysis

Multivariate analysis



Endpoint

Variable

Hazard ratio (95% CI)

p-value

Hazard ratio (95% CI)

p-value


DMFS

14-gene signature

4.34 (1.86–10.1)

0.001

3.64 (1.49–8.90)

0.005

Ki-67 LI

2.40 (1.12–5.11)

0.024

1.55 (0.69–3.45)

0.286


OS

14-gene signature

2.48 (1.42–4.32)

0.001

2.21 (1.23–3.97)

0.008

Ki-67 LI

1.71 (1.00–2.93)

0.049

1.32 (0.75–2.33)

0.332


Tutt et al. BMC Cancer 2008 8:339   doi:10.1186/1471-2407-8-339

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