Figure 8.

Effect of U0126 and PD98059 on MUC2 and NF-κB p65 expression. SEG-1 cells were treated for 18 hours with or without 100 μM DCA in the presence or absence of 8 μM U0126 and 60 μM PD98059. Total cellular and nuclear protein were subjected to Western blotting for MUC2, NF-κB p65, phosphorylation of ERK1/2, JNK, P-38, and total ERK1/2, JNK, P-38 and β-actin.