Open Access Research article

Frameshift mutations in coding repeats of protein tyrosine phosphatase genes in colorectal tumors with microsatellite instability

Sebastian Korff1, Stefan M Woerner1*, Yan P Yuan2, Peer Bork23, Magnus von Knebel Doeberitz1 and Johannes Gebert1

Author Affiliations

1 Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany

2 European Molecular Biology Laboratory, Heidelberg, Germany

3 Max Delbrueck-Centrum for Molecular Medicine, Berlin, Germany

For all author emails, please log on.

BMC Cancer 2008, 8:329  doi:10.1186/1471-2407-8-329

Published: 10 November 2008

Additional files

Additional file 1:

Supplemental material and results information. Table 1 shows the PTP candidate list including primer systems used for the fragment analysis, Tables 2 and 3 present cMNR mutation status information in MSI-H colorectal cancer cell lines and tumors, and Table 4 summarizes the mutation frequencies of the PTP candidate genes in MSI-H colorectal cancer cell lines, tumors, and adenomas.

Format: DOC Size: 307KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data