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Open AccessResearch article

High-resolution array CGH clarifies events occurring on 8p in carcinogenesis

Susanna L Cooke1,2 email, Jessica CM Pole1 email, Suet-Feung Chin2 email, Ian O Ellis3 email, Carlos Caldas2 email and Paul AW Edwards1 email

Department of Pathology and Hutchison/MRC Research Centre, University of Cambridge, Cambridge, UK

CRUK Cambridge Research Institute and Department of Oncology, University of Cambridge, Cambridge, UK

Department of Histopathology, Nottingham City Hospital NHS Trust and University of Nottingham, Nottingham, UK

author email corresponding author email

BMC Cancer 2008, 8:288doi:10.1186/1471-2407-8-288

Published: 7 October 2008

Additional files

Additional File 1:

Cancer cell lines. This file contains Table 1 – a list of all cancer cell lines used in the study, culture conditions and source.

Format: PDF Size: 19KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional File 2:

Validation of 8p array CGH. This file includes the array plot for hybridisation of T47D against normal female on the 8p array platform and FISH validation of the normal copy number polymorphism in 8p23.

Format: PDF Size: 41KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional File 3:

Primers. This file contains Table 2 – a list of the sequences of all primers used in the study.

Format: PDF Size: 10KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional File 4:

8p array CGH. This file includes the data for 38 cancer cell lines for which array CGH was performed on the short arm of chromosome 8.

Format: XLS Size: 360KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional File 5:

Copy number changes on 8p. This file contains Table 3 – a summary of all the copy number changes on 8p identified by array CGH in 38 cancer cell lines.

Format: PDF Size: 20KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional File 6:

Fosmid array CGH. This file includes the fosmid array CGH data for cell lines with rearrangements in either 8p23.3 or 8p22, between DLC1 and TUSC3.

Format: XLS Size: 30KB Download file

This file can be viewed with: Microsoft Excel Viewer


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