|
ORs and 95% CIs for ICC HPV-16EP or AA positive according to HLA. |
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| Controls |
AA Cases |
EP Cases |
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|
|
|
|
|||||
| HLA |
C/N |
C/N |
Crude |
Adjusted |
C/N |
Crude |
Adjusted |
|
|
|
|
|
|
|
|
|
| Controls |
Cases |
OR |
OR (95% CI) |
Cases |
OR |
OR (95% CI) |
|
| n = 257 |
n = 37 |
n = 24 |
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|
|
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| DQA1 |
|||||||
| *0101/04 |
79/178 |
5/32 |
0.35 |
0.34(0.12–0.93) |
9/15 |
1.35 |
1.31 (0.53–3.25) |
| *0102 |
80/177 |
10/27 |
0.82 |
0.82(0.37–1.83) |
12/12 |
2.21 |
2.32 (0.96–5.62) |
| DQB1 |
|||||||
| *0301 |
78/179 |
9/28 |
0.74 |
0.74(0.32–1.70) |
8/16 |
1.15 |
1.08 (0.42–2.75) |
| *05 |
95/162 |
5/32 |
0.27 |
0.27(0.10–0.75) |
10/14 |
1.22 |
1.29 (0.53–3.14) |
| *0501 |
71/186 |
4/33 |
0.32 |
0.30 (0.10–0.92) |
9/15 |
1.57 |
1.56 (0.63–3.89) |
| *06 |
87/170 |
16/21 |
1.49 |
1.49 (0.72–3.08) |
12/12 |
1.95 |
2.02 (0.84–4.88) |
| *0602 |
44/213 |
9/28 |
1.56 |
1.45 (0.62–3.39) |
8/16 |
2.42 |
2.13 (0.83–5.50) |
| DRB1 |
|||||||
| *01 |
52/205 |
4/33 |
0.48 |
0.45 (0.15–1.37) |
7/17 |
1.62 |
1.51 (0.57–4.03) |
| *0102 |
29/228 |
1/36 |
0.22 |
0.18 (0.02–1.44) |
6/18 |
2.62 |
2.18 (0.75–6.29) |
| *04 |
74/183 |
10/27 |
0.92 |
0.94 (0.42–2.09) |
3/21 |
0.35 |
0.34 (0.10–1.21) |
| *13 |
61/196 |
9/28 |
1.03 |
1.21 (0.52–2.78) |
5/19 |
0.85 |
1.09 (0.37–3.16) |
| *1302 |
27/230 |
0/37 |
0.00 |
3/21 |
1.22 |
1.62 (0.42–6.16) |
|
| *15 |
34/223 |
10/27 |
2.43 |
2.34 (1.00–5.46) |
8/16 |
3.28 |
2.99 (1.13–7.86) |
| *1503 |
14/243 |
5/32 |
2.71 |
2.62 (0.83–8.27) |
4/20 |
3.47 |
3.75 (0.99–12.42) |
| DRB1-DQB1 haplotypes |
|||||||
| 0102-0501 |
29/228 |
1/36 |
0.22 |
0.18 (0.02–1.44) |
6/18 |
2.62 |
2.18 (0.75–6.29) |
| 15-0602 |
33/224 |
8/29 |
1.87 |
1.84 (0.75–4.53) |
8/16 |
3.39 |
3.08 (1.17–8.14) |
| 1503-0602 |
14/243 |
5/32 |
2.71 |
2.62 (0.83–8.27) |
4/20 |
3.47 |
3.50 (0.99–12.42) |
| 08041-0301 |
5/252 |
0/27 |
2/22 |
4.58 |
3.59 (0.48–27.13) |
||
| 09012-0201/02 |
3/254 |
1/36 |
2.35 |
2.62 (0.25–27.79) |
1/23 |
3.68 |
5.00 (0.47–53.36) |
de Araujo Souza et al. BMC Cancer 2008 8:246 doi:10.1186/1471-2407-8-246 |
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