Table 2

ORs and 95% CIs for HPV-16 positive ICC according to HLA.


Controls
(n = 257)
HPV-16 Cases
(n = 112)



HLA


Crude
Adjustedd






C/Na
C/N
ORb
OR
CIc

DQA1





          *0102
80/177
39/73
1.18
1.22
0.73–2.04
DQB1





          *0501
71/186
25/87
0.75
0.72
0.40–1.27
     *06
87/170
46/66
1.36
1.32
0.80–2.17
          *0602
44/213
30/82
1.77
1.59
0.89–2.83
DRB1





     *01
52/205
22/90
0.96
0.89
0.49–1.64
          *0102
29/228
12/100
0.94
0.83
0.38–1.79
     *04
74/183
23/89
0.64
0.67
0.38–1.19
     *13
61/196
19/93
0.66
0.78
0.42–1.45
          *1302
27/230
4/108
0.32
0.43
0.14–1.32
DRB1-DQB1 haplotypes





     0102–0501
29/228
12/100
0.94
0.59
0.23–1.51
     15-0602
33/224
28/84
2.26
2.12
1.15–3.93
     1503-0602
14/243
15/97
2.68
2.77
1.20–6.39
     08041-0301
5/252
3/109
1.39
0.88
0.14–5.47
     09012-0201/02
3/254
3/109
2.33
3.02
0.56–16.29

a) C/N: Carriers/Non carriers;

b) OR: Odds Ratio;

c) CI: Confidence Interval;

d) Adjusted for age and ethnic group.

de Araujo Souza et al. BMC Cancer 2008 8:246   doi:10.1186/1471-2407-8-246