Ultrasound can distinguish between different lesions in transgenic mice in vivo. Possible applications are to identify and follow mammary tumor development and progression over time (A-C) and compare to the appearance of tumor at time of necropsy (D), identify liver metastasis (E-F), distinguish between adenocarcinoma (G) and enlarged lymphnodes (H). Thin white arrow: skin surface, thin black arrow: mitotic figure, thick white arrows: liver metastases, circle and black arrow: dissected metastatic lesion, open white arrow: tumor, *: enlarged lymph node. Scale for all ultrasound images in mm.
Tilli et al. BMC Cancer 2008 8:21 doi:10.1186/1471-2407-8-21