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Up-regulation of EGFR ligands in RasV12- and Ras EDM-expressing HME16C |
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| Gene |
V12 |
S35 |
G37 |
C40 |
|
|
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| epiregulin |
2.6 (7.0) |
1.9 (1.0) |
1.8 (2.4) |
1.2 (1.3) |
| TGFa |
3.5 (3.4) |
2.9 (1.3) |
-1.1 (-1.4) |
1.9 (-1.1) |
| amphiregulin |
1.4 (2.4) |
2.9 (1.0) |
2.3 (1.7) |
2.2 (1.0) |
|
Fold up-regulation of the EGFR ligands epiregulin, transforming growth factor alpha (TGFa), and epiregulin in RasV12- and Ras EDM-expressing HME16C as determined by real-time RT-PCR quantification (boldface) and cDNA microarray analysis (in parentheses). | ||||
Oberst et al. BMC Cancer 2008 8:189 doi:10.1186/1471-2407-8-189 |
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