|
Patient characteristics and enzymes activities |
||||
| Factor |
n |
TS activity Tumor: Normal colon |
DPDS activity Tumor: Normal colon |
OPRT activity Tumor: Normal colon |
|
|
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| Mean Age: |
40 |
10.8 ± 8.0 2.1 ± 1.2 |
28.1 ± 24.0 29.9 ± 14.6 |
0.50 ± 0.11 0.23 ± 0.07 |
| Age: |
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| young < 69 |
24 |
11.6 ± 8.7 2.6 ± 0.8 |
30.5 ± 28.9 28.6 ± 14.8 |
0.54 ± 0.10 0.20 ± 0.09 |
| Old > 70 |
16 |
10.0 ± 8.1 1.6 ± 1.8 |
27.2 ± 20.7 30.7 ± 12.1 |
0.48 ± 0.14 0.25 ± 0.05 |
| Gender: |
||||
| male |
23 |
12.1 ± 9.8 2.2 ± 1.4 |
25.8 ± 27.7 28.8 ± 15.8 |
0.54 ± 0.13 0.20 ± 0.09 |
| Female |
17 |
9.9 ± 9.5 2.0 ± 1.1 |
32.3 ± 21.3 30.6 ± 11.2 |
0.49 ± 0.12 0.24 ± 0.07 |
| Histological type |
||||
| Well |
22 |
11.90 ± 5.6 2.3 ± 1.0 |
26.9 ± 21.8 31.8 ± 15.9 |
0.56 ± 0.12 0.20 ± 0.11 |
| Moderately |
18 |
10.0 ± 11.8 1.9 ± 1.5 |
30.5 ± 25.9 27.6 ± 11.8 |
0.45 ± 0.14 0.23 ± 0.05 |
| Nodal status |
||||
| N(-) |
22 |
9.5 ± 10.2 2.7 ± 1.8 |
27.9 ± 27.8 32.0 ± 12.1 |
0.65 ± 0.11* 0.22 ± 0.08 |
| N(+) |
18 |
12.5 ± 6.9 1.5 ± 0.8 |
30.0 ± 22.8 26.5 ± 17.2 |
0.41 ± 0.13* 0.23 ± 0.07 |
| Tumor depth |
||||
| s.s. |
26 |
10.0 ± 6.7 1.9 ± 0.9 |
27.5 ± 19.8 32.8 ± 11.5 |
0.54 ± 0.13 0.23 ± 0.08 |
| s.e. |
14 |
12.1 ± 9.8 2.3 ± 1.8 |
29.2 ± 29.7 26.1 ± 15.3 |
0.48 ± 0.11 0.23 ± 0.08 |
| Tumor size |
||||
| > 5.0 cm |
27 |
9.5 ± 6.6 2.6 ± 1.0 |
27.7 ± 27.8 35.7 ± 19.9 |
0.54 ± 0.13 0.22 ± 0.07 |
| < 4.9 cm |
13 |
12.5 ± 9.5 1.7 ± 1.9 |
30.9 ± 20.8 23.9 ± 9.9 |
0.48 ± 0.12 0.23 ± 0.09 |
|
s.s.: histological tumor invasion of subserosa, s.e.: histological tumor invasion of serosa *P < 0.05 (p mol/min/mg-protein) Values represent mean ± SD. | ||||
Ishikawa et al. BMC Cancer 2008 8:188 doi:10.1186/1471-2407-8-188 |
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