Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level

doi:10.1186/1471-2407-8-187

BMC Cancer
Volume 8

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Macartney-Coxson DP
Hood KA
Shi H
Ward T
Wiles A
O'Connor R
Hall DA
Lea RA
Royds JA
Stubbs RS
Rooker S

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Macartney-Coxson DP
Hood KA
Shi H
Ward T
Wiles A
O'Connor R
Hall DA
Lea RA
Royds JA
Stubbs RS
Rooker S
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Research article

Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level

Donia P Macartney-Coxson¹^,2 , Kylie A Hood¹ , Hong-jun Shi¹ , Teresa Ward¹ , Anna Wiles³ , Rosemary O'Connor⁴ , David A Hall² , Rod A Lea² , Janice A Royds³ , Richard S Stubbs¹ and Serena Rooker¹^,5

¹Wakefield Gastroenterology Research Institute, Wellington, New Zealand

²Institute of Environmental Science and Research, Kenepuru Science Centre, Porirua, New Zealand

³Dunedin School of Medicine, University of Otago, Dunedin, New Zealand

⁴Cell Biology Laboratory, Department of Biochemistry, University College Cork, Cork, Ireland

⁵Capital and Coast Health, Wellington Hospital, Wellington, New Zealand

author email corresponding author email

BMC Cancer 2008, 8:187doi:10.1186/1471-2407-8-187


Published:	1 July 2008

Additional files

Additional file 1:

Assays from ABI used for real-time PCR.

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Additional file 2:

Oligonucleotide primers and annealing temperatures.

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Additional file 3:

25 protein-coding genes encoded by 2 Mb region of MSL.

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Additional file 4:

Gene expression data (Mean dCt and SEM) for all genes investigated.

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Additional file 5:

Immunohistochemistry of PDLIM2.

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Additional file 6:

Gene:gene mRNA expression correlations in CT and matched LM.

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