|
Associations (χ2-tests/Fischers exact test) between the protein expression of ADAM9 in renal cell cancer and clinico-pathological parameters (percentages in brackets) |
||||
| Total |
low ADAM9 |
high ADAM9 |
p-value |
|
|
|
||||
| All cases |
108 (100) |
71 (65.7) |
37 (34.3) |
|
| Age |
0.225 |
|||
| ≤ 62 |
59 (54.6) |
42 (71.2) |
17 (28.8) |
|
| > 62 |
49 (45.4) |
29 (59.2) |
20 (40.8) |
|
| Histology |
< 0.001 |
|||
| Clear cell |
86 (79.6) |
65 (75.6) |
21 (24.4) |
|
| chromophobe |
5 (4.6) |
2 (40.0) |
3 (60.0) |
|
| Papillary |
17 (15.7) |
4 (23.4) |
13 (76.5) |
|
| pT-status |
0.104 |
|||
| pT1 |
54 (50.0) |
40 (74.1) |
14 (25.9) |
|
| pT2/3/4 |
54 (50.0) |
31 (57.4) |
23 (42.6) |
|
| pN-status* |
0.022 |
|||
| pN0 |
51 (47.2) |
36 (70.6) |
15 (29.4) |
|
| pN1 |
12 (11.1) |
4 (33.3) |
8 (66.7) |
|
| Grading |
0.002 |
|||
| G 1 |
11 (10.2) |
11(100) |
0 (0) |
|
| G 2 |
75 (69.4) |
50 (66.7) |
25 (33.3) |
|
| G 3/4 |
22 (20.4) |
10 (45.5) |
12 (54.5) |
|
| Residual tumour status# |
0.073 |
|||
| R0 |
78 (72.2) |
56 (71.8) |
22 (28.2) |
|
| R1/2 |
15 (13.9) |
7 (46.7) |
8 (53.3) |
|
| Metastasis |
0.014 |
|||
| M0 |
85 (78.7) |
61 (71.8) |
24 (28.2) |
|
| M1 |
23 (21.3) |
10 (43.5) |
13 (56.5) |
|
|
* 45 cases were pNx # 15 cases were Rx | ||||
Fritzsche et al. BMC Cancer 2008 8:179 doi:10.1186/1471-2407-8-179 |
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