|
Proportion of predictive tests positive in unaffected FDR women >50 years of age by family Manchester score for each gene |
||
| Manch score predictives |
Above or = |
Below |
|
|
||
| (score) |
% positive |
% positive |
| BRCA2 >50 (23) |
9/37 (24%) |
9/24 (37.5%) |
| BRCA2 >50 (20) |
10/44 (23%)* |
8/17 (47%)* |
| BRCA1 >50 (23) |
7/33 (21%) |
5/20 (20%) |
| BRCA1 >50 (20) |
8/39 (20.5%) |
4/14 (29%) |
|
*chi square for difference 3.48; p = 0.07 | ||
Evans et al. BMC Cancer 2008 8:155 doi:10.1186/1471-2407-8-155 |
||