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Open AccessHighly AccessResearch article

Meta-analysis confirms BCL2 is an independent prognostic marker in breast cancer

Grace M Callagy1 email, Mark J Webber1 email, Paul DP Pharoah2 email and Carlos Caldas3 email

1Department of Pathology, National University of Ireland, Galway, Clinical Science Institute, Costello Road, Galway, Ireland

2Cancer Research-UK Department of Oncology, Cancer Research-UK Genetic Epidemiology Unit and EPIC, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK

3Department of Oncology, University of Cambridge and Cancer Research-UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge CB2 0RE, UK

author email corresponding author email

BMC Cancer 2008, 8:153doi:10.1186/1471-2407-8-153

Published: 29 May 2008

Additional files

Additional file 1:

Table of 36 studies excluded from the meta-analysis. table summarising the 36 studies excluded from the meta-analysis on the basis of small study size and the provision of insufficient data for the pooled analysis.

Format: XLS Size: 33KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 2:

References for 36 studies excluded from meta-analysis. References for the 36 studies summarised in additional file 1 that were excluded from meta-analysis.

Format: DOC Size: 33KB Download file

This file can be viewed with: Microsoft Word Viewer

Additional file 3:

Reports examining the association between expression of BCL2 and DFS and/or OS that include over 100 cases of breast cancer. table summarising the 17 reports included for the meta-analysis.

Format: DOC Size: 67KB Download file

This file can be viewed with: Microsoft Word Viewer

Additional file 4:

Results of univariate and multivariate analyses for OS and DFS for 17 studies included in the meta-analysis. table summarising the results of univariate and multivariate analysis in 17 reports included for the meta-analysis.

Format: DOC Size: 68KB Download file

This file can be viewed with: Microsoft Word Viewer


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