|
CDH1 intron 2 haplotype frequencies among DGA cases and controls |
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| Case (freq)† |
Control (freq)† |
Fisher's p |
Pearson's p |
OR (95%CI) |
|
|
|
|||||
| AAC* |
16.04 (0.060) |
5.31 (0.027) |
0.088 |
0.088 |
2.33 (0.86–6.34) |
| AAG |
17.49 (0.065) |
5.34 (0.027) |
0.056 |
0.056 |
2.55 (0.95–6.83) |
| ATC |
73.09 (0.273) |
35.43 (0.177) |
0.015 |
0.015 |
1.74 (1.11–2.74) |
| ATG |
45.38 (0.169) |
29.91 (0.150) |
0.565 |
0.565 |
1.16 (0.70–1.92) |
| GAC |
21.73 (0.081) |
24.18 (0.121) |
0.152 |
0.152 |
0.64 (0.35–1.18) |
| GAG |
17.75 (0.066) |
22.17 (0.111) |
0.087 |
0.087 |
0.57 (0.30–1.09) |
| GTC |
39.15 (0.146) |
53.07 (0.265) |
0.001 |
0.001 |
0.47 (0.30–0.75) |
| GTG |
37.37 (0.139) |
24.85 (0.123) |
0.602 |
0.602 |
1.16 (0.67–1.99) |
|
*Haplotype order: 163+37235G>A, 163+37276T>A, 163+49526C>G. The two 5'-variants were not included, as they did not further split up the haplotypes. †Numbers refer to reconstructed haplotype numbers among cases (257) and controls (192), with each individual carrying two chromosomes. Relative frequencies are given in percent. Not all genotype data was included into analysis, as low frequency haplotypes were dropped. | |||||
Nasri et al. BMC Cancer 2008 8:138 doi:10.1186/1471-2407-8-138 |
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