Table 2

Serum levels (mmol/L) of β-OHB in tumour-bearing animals of the KD and SD groups on different days after tumour cell injection (day 0).

KD

Days after tumour cell inoculation

0

6

8

20

23

28

Mean

0.5

0.9 *

1.2 *

1.6 *

1.3 *

1.2 *

± SD

0.1

0.2

0.2

0.6

0.4

0.3

SD

Days after tumour cell inoculation

0

6

8

20

23

28

Mean

0.5

0.5

0.5

0.6

0.7

0.6

± SD

0.09

0.09

0.07

0.06

0.08

0.06

KD animals achieved ketosis within 6 days after feeding the ketogenic diet (Table 1) and remained significantly higher than those of SD animals (* P < 0.001). In contrast, serum glucose levels were not significantly different between SD and KD animals (see Results).

Otto et al. BMC Cancer 2008 8:122   doi:10.1186/1471-2407-8-122