Size of the necrotic areas (in black) in tumours of animals of the KD (animals 1–12) and SD (animals 13–24) groups. The total area of necrosis per section was quantified and expressed as the percentage to the total area of the section as described in Methods. Tumours of the KD group had significantly larger areas of necrosis than tumours of the SD group (P = 0.0074). A representative H&E histology for KD and SD animals is shown.
Otto et al. BMC Cancer 2008 8:122 doi:10.1186/1471-2407-8-122